Body fluids 1 and 2 linda costanzo phd. Fluid loss in sweat 100 mlday 3.
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Measurement of body fluid compartments pdf. If you measure too soon all you will get is the volume of the functional extracellular fluid. Theoretically its possible to measure the size of each of the body fluid compartments by injecting substances that will stay in one compartment only the substance that attach to object that only exist in interested fluid like plasma protein only exist in plasma and cannot escape and then calculate the volume of fluid in which the test substance is distributed volume of distribution of. A marker is injected that will be evenly distributed in all the compartments of body fluids. Thus bromine measurements of the ecf volume frequently over estimate the ecf volume. If the tracer is metabolised a series of measurements can be made and assuming exponential decline first order kinetics the volume of distribution can be determined by extrapolation back to zero time. After studying this lecture the student should understand.
The intracellular fluid icf compartment is the system that includes all fluid enclosed in cells by their plasma membranes. It does not matter about size and compositionif you can count every particle in that compartment in all the. Measuring the extracellular fluid volume with crystalloid tracer. Fluid intake and output daily intake of water 1. Not interfere with body fluid distribution if the tracer is excreted in the urine then the loss can be determined and corrections made in the calculation. The distribution of water between the major body fluid compartments.
Unfortunately some bromine 82 also distributes into the cells. Of physiology body fluids 2. Body fluid compartments have different sizes and volumes and different compositions. 18112012 14 copyright 2004 pearson education inc publishing as benjamin cummings. How to measure the volumes of body fluid compartments using marker substances. Insensible water loss 700 mlday 2.
Body fluids can be discussed in terms of their specific fluid compartment a location that is largely separate from another compartment by some form of a physical barrier. Measurement of each compartment 4. If you manipulate one body fluid compartment it has an effect on another compartment. Significance of body fluids. Synthesis in the body as a result of oxidation of carbohydrates adding about 200 mlday daily loss of body water 1. Liquids or water in the food 2100 mlday 2.
Sinan canan created date. Measurement of body fluid volumes total body water is measured using dilution principle. Water loss in feces 100 mlday 4. What is dissolved in the fluid is different. The differences in composition between the major body fluid compartments. Water balance positive and negative water balance 6.
Volumes compartments of body fluids 2. Marker that diffuses freely not only in the water outside the cells but also crosses the cell membrane to reach the intracellular fluid. Dr nilesh kate mbbsmd associate prof dept. Composition of body fluids 3.
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